Folklore MCP is Helena Bioinformatics' public bioinformatics interface for gene identities, genomic variant evidence and scientific literature. Its hosted Streamable HTTP endpoint is https://api.helena.bio/folklore/v1/mcp and requires no account or API key. It supports public gene/disease identifiers and supported GRCh38 germline variant expressions, rather than raw sequencing files or patient genome analysis. Setup and current capabilities: https://folklore.helena.bio/integrations/mcp . The public adapter repository is Apache-2.0 licensed; this does not open-source the clinical backend or its evidence database. See https://github.com/helena-bioinformatics/folklore-mcp . Preserve returned source citations, evidence limitations, immutable snapshot identifiers and ambiguous or unavailable results. Public evidence and automated assessments require qualified professional review and are not diagnosis or treatment advice. Do not send patient identifiers or private case data. Verification on November 1, 2026: the no-auth MCP initialized and listed 11 tools, including gene resolution, gene profiles, gene-disease associations, literature search and a separate support helper. A real resolve_gene call for the public symbol BRCA1 returned an exact HGNC:1100 identity and snapshot ID. No patient data, variant classification, clinical accuracy, private account workflow or paid operation was tested. The public endpoint is free; this listing does not imply that every Helena platform feature is free.
Best for agent capabilities
Useful in agent tasks
Overview
When to use Folklore Clinical Variant Interpretation MCP
Folklore Clinical Variant Interpretation MCP is listed for Data, Search workflows. Folklore MCP is Helena Bioinformatics' public bioinformatics interface for gene identities, genomic variant evidence and scientific literature. Its hosted Streamable HTTP endpoint is https://api.helena.bio/folklore/v1/mcp and requires no account or API key. It supports public gene/disease identifiers and supported GRCh38 germline variant expressions, rather than raw sequencing files or patient genome analysis. Setup and current capabilities: https://folklore.helena.bio/integrations/mcp . The public adapter repository is Apache-2.0 licensed; this does not open-source the clinical backend or its evidence database. See https://github.com/helena-bioinformatics/folklore-mcp . Preserve returned source citations, evidence limitations, immutable snapshot identifiers and ambiguous or unavailable results. Public evidence and automated assessments require qualified professional review and are not diagnosis or treatment advice. Do not send patient identifiers or private case data. Verification on November 1, 2026: the no-auth MCP initialized and listed 11 tools, including gene resolution, gene profiles, gene-disease associations, literature search and a separate support helper. A real resolve_gene call for the public symbol BRCA1 returned an exact HGNC:1100 identity and snapshot ID. No patient data, variant classification, clinical accuracy, private account workflow or paid operation was tested. The public endpoint is free; this listing does not imply that every Helena platform feature is free. Consider it when an agent needs this capability through a documented service boundary instead of custom infrastructure maintained inside the application.
In 4agent’s task model, the product maps to Web search, Web extraction, Workflow automation. That makes it a candidate for these tasks: Research the web, Manage memory and knowledge, Communicate with users, Automate business workflows.
Integration checklist
- Access: Confirm the none authentication flow, credential scope, rotation process, and whether calls can be attributed to a user or service identity.
- Client support: No SDK is recorded, so verify the HTTP API or another supported integration path.
- Automation: OpenAPI: not currently recorded; MCP: listed as available; CLI: not currently recorded. Confirm each requirement in the provider's current documentation.
- Operations: Test rate limits, timeouts, retry safety, error payloads, logs, data retention, and the current free-tier and paid pricing model with production-like volume.
Sources and verification
Use these primary sources to verify current behavior before making an implementation or purchasing decision. Product capabilities, limits, and prices can change after a 4agent listing is reviewed.